Vitamin B1 - Bioavailability
Introduction
Vitamin B1 is a water-soluble and is well absorbed into and excreted from the human body.
Bioavailability [1]
Oral Absorption
Vitamin B1 is relatively well absorbed when consumed orally.
Oral Vitamin B1 is absorbed via the upper and lower Small Intestine. The Small Intestine absorbs Vitamin B1 via two mechanisms: active transport (2 µmol/L). A specific Sodium-dependent and Energy-dependent carrier appears to exist:
The primary sites of Vitamin B1 absorption in the Small Intestine are the Jejunum and the Ileum.
The (lipid-soluble) Benfotiamine form of Vitamin B1 may have better bioavailability compared with other forms of Vitamin B1.
The Sulbutiamine form of Vitamin B1 is rapidly absorbed via the oral route. Its blood concentration peaks 1 – 2 hours after oral administration.
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