CYP2C19

1 min readEvidence-linked topicGreen Medicine Encyclopedia

Also known as:  Cytochrome P-4502C19

 

Description

CYP2C19 is a type of Cytochrome P-450 Enzyme.

 

Function of CYP2C19

 Like all Cytochrome P-450 enzymes, CYP2C19 is responsible for the (Phase I) detoxification of various substances in the Liver.  The following substances are acted upon by 2C19:

 

Hormones

 Progesterone

 

Prescribed Medications

 Amitriptiline

 Carisoprodol

 Citalopram

 Clomipramine

 Cyclophosphamide

 Diazepam

 Dilantin

 Hexoabarbital

 Imipramine

 Indomethacin

 Lansoprazole

 Mephobarbital

 Nevirapine

 Nilutamide

 Omeprazole

 Pantoprazole

 Primidone

 Proguanil

 Propranolol

 Ritonavir

 Teniposide

 Valproic Acid

 Warfarin

 

These Herbs may Increase the Activity of CYP2C19

 Ginkgo biloba may increase the activity of CYP2C19.  [1]

 

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